The HM13 Antibody (C-term) from MyBioSource.com is a Rabbit Polyclonal antibody to HM13, and SPP. This antibody recognizes Human antigen. The HM13 Antibody (C-term) has been validated for the following applications: ELISA, and Western Blot.
Description
The protein encoded by this gene, which localizes to the
endoplasmic reticulum, catalyzes intramembrane proteolysis of some
signal peptides after they have been cleaved from a preprotein.
This activity is required to generate signal sequence-derived human
lymphocyte antigen-E epitopes that are recognized by the immune
system, and to process hepatitis C virus core protein. The encoded
protein is an integral membrane protein with sequence motifs
characteristic of the presenilin-type aspartic proteases. Multiple
transcript variants encoding several different isoforms have been
found for this gene